Source record

Published by arXiv cs.MA (T1 source). The original is at https://arxiv.org/abs/2609.05496.

Pipeline notes

The summary and note below are generated by the signal pipeline — they are Beyond Desk’s reading, not quotations from the source.

A multi-agent bioinformatics system (Orchestra) that composes two MCP servers — RegNetAgents for gene regulatory network topology and CASCADE for four experimental evidence sources — to identify cancer gene regulators. Tests whether requiring agreement between computational topology and experimental evidence yields more trustworthy candidates than either alone, validating on TCGA BRCA, COAD, and STAD panels against OncoKB and COSMIC ground truth.

Concrete corroboration pattern for multi-agent workflows: require independent evidence sources to agree before flagging a candidate. Useful methodological reference for filtering noisy single-source agent outputs.

Cited by

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